Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 9/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | PRKCB | P05771 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25377299 | 0.94 | PDE10A (0.46) | PDE10AADORA2AADORA2BADORA1 | |
| SCHEMBL25377440 | 0.90 | PDE10A (0.42) | PDE10APRKCBGSK3B | |
| SCHEMBL25377875 | 0.89 | PDE10A (0.44) | PDE10A | |
| SCHEMBL25432558 | 0.89 | PDE10A (0.47) | PDE10A | |
| SCHEMBL25377138 | 0.88 | PDE10A (0.43) | PDE10A | |
| SCHEMBL25377379 | 0.87 | PDE10A (0.41) | PDE10A | |
| SCHEMBL25374898 | 0.86 | PDE10A (0.45) | PDE10AADORA2AADORA2BADORA1 | |
| SCHEMBL25378665 | 0.84 | PDE10A (0.39) | PDE10A | |
| SCHEMBL25377580 | 0.83 | PDPK1 (0.44) | PDE10APRKCBGSK3B | |
| SCHEMBL25373725 | 0.82 | PDE10A (0.50) | PDE10AADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146512-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146512-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |