SCHEMBL25378665

SCHEMBL25378665

O=c1ccc(-c2cccnc2Oc2ccc(S(F)(F)(F)(F)F)cc2)cn1CC(F)F

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ PDE10A Q9Y233 5/20 0.39
▸ FEN1 P39748 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25374898 0.88 PDE10A (0.45) PDE10A
SCHEMBL25377875 0.87 PDE10A (0.44) PDE10AFEN1
SCHEMBL25432558 0.87 PDE10A (0.47) PDE10A
SCHEMBL25377138 0.86 PDE10A (0.43) PDE10AFEN1
SCHEMBL25377299 0.86 PDE10A (0.46) PDE10A
SCHEMBL25377440 0.84 PDE10A (0.42) PDE10AFEN1
SCHEMBL25374074 0.84 PDE10A (0.44) PDE10A
SCHEMBL26204849 0.82 PDE10A (0.43) PDE10AFEN1
SCHEMBL25373725 0.82 PDE10A (0.50) PDE10A
SCHEMBL25377379 0.80 PDE10A (0.41) PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023146512-A1 COMPOUNDS AND METHODS OF USE THEREOF VIVACE THERAPEUTICS, INC. (US) 2023-08-03 — — WO disclosed
WO-2023146512-A1 COMPOUNDS AND METHODS OF USE THEREOF VIVACE THERAPEUTICS, INC. (US) 2023-08-03 — — WO disclosed
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