Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PAICS | P22234 | 1/20 | 0.38 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19650813 | 0.94 | KDM1A (0.59) | KDM1AMAOBMAOAHDAC1HDAC8 | |
| SCHEMBL29456936 | 0.94 | KDM1A (0.59) | KDM1AMAOBMAOAHDAC1HDAC8 | |
| Hydrochloric Acid SCHEMBL30615191 | 0.93 | KDM1A (0.58) | KDM1AMAOBMAOAHDAC1HDAC8 | |
| SCHEMBL23545585 | 0.88 | KDM1A (0.56) | KDM1AMAOBMAOAHDAC1HDAC8 | |
| SCHEMBL30471935 | 0.88 | KDM1A (0.56) | KDM1AMAOBMAOAHDAC1HDAC8 | |
| SCHEMBL24468271 | 0.84 | KDM1A (0.53) | KDM1AMAOBMAOAHDAC1HDAC8 | |
| SCHEMBL22787428 | 0.82 | KDM1A (0.47) | KDM1AMAOBMAOAHDAC1HDAC8 | |
| SCHEMBL31137369 | 0.80 | KDM1A (0.54) | KDM1AMAOBMAOAHDAC1HDAC8 | |
| SCHEMBL22787439 | 0.80 | KDM1A (0.45) | KDM1AMAOBMAOAHDAC1HDAC8 | |
| SCHEMBL31613889 | 0.79 | KDM1A (0.47) | KDM1AMAOBMAOANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146987-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |