Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.64 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PNLIP | P16233 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30530136 | 0.93 | SCN8A (0.66) | SCN8ASCN10ANPC1MAPTHPGD | |
| SCHEMBL20644052 | 0.93 | SCN8A (0.66) | SCN8ASCN10ANPC1MAPTHPGD | |
| SCHEMBL21130032 | 0.85 | SCN8A (0.71) | SCN8ASCN10ANPC1MAPTHPGD | |
| SCHEMBL20644073 | 0.85 | SCN8A (0.56) | SCN8ASCN10ANPC1MAPTHPGD | |
| SCHEMBL31297250 | 0.85 | SCN8A (0.56) | SCN8ASCN10ANPC1MAPTHPGD | |
| SCHEMBL16408392 | 0.83 | SCN8A (0.64) | SCN8ASCN10A | |
| SCHEMBL15561702 | 0.81 | SCN8A (0.68) | SCN8ASCN10A | |
| SCHEMBL26360385 | 0.79 | SCN8A (0.64) | SCN8ASCN10ANPC1MAPTHPGD | |
| SCHEMBL20644033 | 0.79 | KCNK3 (0.53) | SCN8ASCN10AMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL26360106 | 0.79 | SCN8A (0.65) | SCN8ASCN10ANPC1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023160509-A1 | AMIDINE DERIVATIVE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院上海药物研究所 | 2023-08-31 | — | — | WO | disclosed |