Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.56 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20644073 | 1.00 | SCN8A (0.56) | SCN8ASCN10ANPC1RAB9AMEN1 | |
| SCHEMBL20644052 | 0.92 | SCN8A (0.66) | SCN8ASCN10ANPC1RAB9AMAPT | |
| SCHEMBL30530136 | 0.92 | SCN8A (0.66) | SCN8ASCN10ANPC1RAB9AMAPT | |
| SCHEMBL20644033 | 0.90 | KCNK3 (0.53) | SCN8ASCN10ARAB9AMEN1KMT2A | |
| SCHEMBL20644046 | 0.85 | SCN8A (0.66) | SCN8ASCN10AMAPT | |
| SCHEMBL31297281 | 0.85 | SCN8A (0.66) | SCN8ASCN10AMAPT | |
| SCHEMBL25375191 | 0.85 | SCN8A (0.64) | SCN8ASCN10ANPC1RAB9AMAPT | |
| SCHEMBL16408396 | 0.85 | — | — | |
| SCHEMBL20644107 | 0.84 | SCN8A (0.62) | SCN8ASCN10A | |
| SCHEMBL20638927 | 0.82 | SCN8A (0.52) | SCN8ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3651752-B1 | CARBOXAMIDES AS MODULATORS OF SODIUM CHANNELS | VERTEX PHARMA (US) | 2024-11-20 | — | — | EP | disclosed |