SCHEMBL25375392

SCHEMBL25375392

O=P(O)(O)CCOCCCl

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TYMS P04818 1/20 0.46
ALDH1A1 P00352 2/20 0.40
LMNA P02545 1/20 0.33
CYP3A4 P08684 1/20 0.33
NFKB1 P19838 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
HPRT1 P00492 3/20 0.31
LPAR3 Q9UBY5 3/20 0.31
LPAR2 Q9HBW0 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MMP2 P08253 1/20 0.30
THRB P10828 1/20 0.30
MAPK1 P28482 1/20 0.30
HSD17B10 Q99714 1/20 0.30
BBOX1 O75936 1/20 0.30
GRM4 Q14833 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9498785 0.87 TYMS (0.50) TYMSALDH1A1LMNACYP3A4NFKB1
SCHEMBL9302274 0.84 TYMS (0.47) TYMSALDH1A1LMNACYP3A4NFKB1
SCHEMBL15281284 0.77 TSHR (0.53) TYMSALDH1A1LMNACYP3A4NFKB1
SCHEMBL1029592 0.77
SCHEMBL3216201 0.75 TYMS (0.39) TYMSALDH1A1LMNACYP3A4NFKB1
SCHEMBL20958148 0.75 MEN1 (0.55) TYMSALDH1A1LMNACYP3A4NFKB1
SCHEMBL6224646 0.75 MEN1 (0.55) TYMSALDH1A1LMNACYP3A4NFKB1
SCHEMBL22711008 0.75 MEN1 (0.55) TYMSALDH1A1LMNACYP3A4NFKB1
SCHEMBL16007815 0.75 MEN1 (0.55) TYMSALDH1A1LMNACYP3A4NFKB1
SCHEMBL16625419 0.75 TYMS (0.39) TYMSALDH1A1LMNACYP3A4NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230248837-A1 Technology for Modulating Targeting Chimeras Induced by Cell-Penetrating Peptide and Application Thereof LIU, MIAO (CN) 2023-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230248837-A1 Technology for Modulating Targeting Chimeras Induced by Cell-Penetrating Peptide and Application Thereof VIP, GHITM, MYCBP TYMS 2637/4885ALDH1A1 4851/4885LMNA 3791/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.