Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | NOS3 | P29474 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | BCR | P11274 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25377311 | 0.86 | S1PR1 (0.45) | ABL1BCRTAS2R14EPHX2MAPK8 | |
| SCHEMBL25375951 | 0.84 | KCNH2 (0.49) | ABL1BCRMAPTKDM4EKCNH2 | |
| SCHEMBL30482552 | 0.84 | EGFR (0.47) | DYRK1ANOS3NOS2ABL1BCR | |
| SCHEMBL26202876 | 0.84 | EGFR (0.47) | DYRK1ANOS3NOS2ABL1BCR | |
| SCHEMBL25377886 | 0.82 | KCNH2 (0.45) | ABL1BCRALDH1A1KCNH2TAS2R14 | |
| SCHEMBL30482511 | 0.82 | KCNH2 (0.45) | ABL1BCRALDH1A1KCNH2TAS2R14 | |
| SCHEMBL30482527 | 0.81 | MAPK8 (0.41) | DYRK1AABL1BCRMAPTTAS2R14 | |
| SCHEMBL25376686 | 0.81 | MAPK8 (0.41) | DYRK1AABL1BCRMAPTTAS2R14 | |
| SCHEMBL20779733 | 0.80 | DYRK1A (0.42) | DYRK1ANOS3NOS2ABL1BCR | |
| SCHEMBL21053184 | 0.80 | AKR1C3 (0.48) | DYRK1AABL1BCRALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146512-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146512-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |