Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30482552 | 1.00 | EGFR (0.47) | EGFRDYRK1AEPHX2ABL1BCR | |
| SCHEMBL25375552 | 0.84 | DYRK1A (0.48) | EGFRDYRK1AEPHX2ABL1BCR | |
| SCHEMBL25339314 | 0.82 | TRPV1 (0.46) | EGFREPHX2TRPV1ABCG2 | |
| SCHEMBL25956232 | 0.81 | KDM4E (0.43) | EGFREPHX2TRPV1 | |
| SCHEMBL25956364 | 0.80 | TRPV1 (0.45) | EGFREPHX2TRPV1ABCG2LMNA | |
| SCHEMBL25338503 | 0.78 | TRPV1 (0.53) | EGFRDYRK1ATRPV1 | |
| SCHEMBL25974137 | 0.78 | TRPV1 (0.49) | EPHX2TRPV1 | |
| SCHEMBL25974136 | 0.78 | EPHX2 (0.48) | EPHX2TRPV1 | |
| SCHEMBL25974055 | 0.78 | EPHX2 (0.46) | EPHX2TRPV1LMNA | |
| SCHEMBL25956271 | 0.77 | EPHX2 (0.41) | EGFREPHX2TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146512-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |