Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | TTK | P33981 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30558711 | 1.00 | POLB (0.39) | POLBL3MBTL1MAPTNPSR1KMT2A | |
| SCHEMBL23832162 | 0.85 | POLB (0.47) | POLBL3MBTL1MAPTNPSR1KMT2A | |
| SCHEMBL17450949 | 0.84 | CA2 (0.42) | POLBL3MBTL1MAPTNPSR1CA2 | |
| SCHEMBL8000890 | 0.83 | POLB (0.36) | POLBL3MBTL1MAPTNPSR1KMT2A | |
| SCHEMBL30103969 | 0.83 | POLB (0.50) | POLBL3MBTL1MAPTNPSR1NQO2 | |
| SCHEMBL16914277 | 0.82 | POLB (0.35) | POLBL3MBTL1MAPTNPSR1KMT2A | |
| SCHEMBL26927378 | 0.82 | GSK3A (0.39) | POLBL3MBTL1MAPTNPSR1GSK3A | |
| SCHEMBL31500457 | 0.82 | GSK3A (0.39) | POLBL3MBTL1MAPTNPSR1GSK3A | |
| SCHEMBL21620481 | 0.77 | CCNA2 (0.42) | POLBL3MBTL1MAPTNPSR1KMT2A | |
| SCHEMBL12682543 | 0.77 | KDM4E (0.51) | POLBL3MBTL1MAPTNPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164181-A1 | BENZOTHIA(DIA)ZEPINE COMPOUNDS FOR TREATMENT OF HBV AND HDV | ASSEMBLY BIOSCIENCES, INC. (US) | 2023-08-31 | — | — | WO | disclosed |
| WO-2023164181-A1 | BENZOTHIA(DIA)ZEPINE COMPOUNDS FOR TREATMENT OF HBV AND HDV | ASSEMBLY BIOSCIENCES, INC. (US) | 2023-08-31 | — | — | WO | disclosed |