Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 2/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5690888 | 0.84 | CA1 (0.52) | CA1P2RX7ALDH1A1CTSDNAMPT | |
| SCHEMBL7498699 | 0.81 | — | — | |
| SCHEMBL17919914 | 0.79 | CA1 (0.40) | CA1P2RX7ALDH1A1CTSDNAMPT | |
| SCHEMBL25695856 | 0.77 | CA1 (0.46) | CA1P2RX7ALDH1A1CTSDNAMPT | |
| SCHEMBL20711252 | 0.76 | CA1 (0.44) | CA1P2RX7ALDH1A1CTSDNAMPT | |
| SCHEMBL14453257 | 0.76 | CA1 (0.44) | CA1P2RX7ALDH1A1CTSDNAMPT | |
| SCHEMBL29284706 | 0.74 | CA1 (0.43) | CA1P2RX7ALDH1A1CTSDNAMPT | |
| SCHEMBL23978712 | 0.74 | CA1 (0.43) | CA1P2RX7ALDH1A1CTSDNAMPT | |
| SCHEMBL8630866 | 0.74 | GSR (0.52) | FOLH1 | |
| SCHEMBL13701374 | 0.72 | CA1 (0.41) | CA1P2RX7ALDH1A1CTSDNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4486452-A1 | INHIBITORS OF PSEUDOMONAS AERUGINOSA VIRULENCE FACTOR LASSS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2025-01-08 | — | — | EP | disclosed |
| WO-2023166039-A1 | INHIBITORS OF PSEUDOMONAS AERUGINOSA VIRULENCE FACTOR Lasß | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-09-07 | — | — | WO | disclosed |