Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.52 |
| ▸ | GRM8 | O00222 | 1/20 | 0.52 |
| ▸ | GRM6 | O15303 | 1/20 | 0.52 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.52 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.52 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.52 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.52 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.52 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.52 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.52 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31562940 | 0.86 | GSR (0.62) | GSRGRM8GRM6GRIN2DGRIN3B | |
| Glutamine Hydroxamate SCHEMBL7645305 | 0.84 | GSR (0.67) | GSRGRM8GRM6GRIN2DGRIN3B | |
| Glutamine Hydroxamate SCHEMBL4321249 | 0.84 | GSR (0.67) | GSRGRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL28229088 | 0.82 | GSR (0.58) | GSRGRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL7049981 | 0.80 | ALOX15 (0.59) | GSRGRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL27890690 | 0.80 | ALOX15 (0.59) | GSRGRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL4175471 | 0.78 | GSR (0.54) | GSRGRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL2909135 | 0.78 | GRM8 (0.54) | GSRGRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL467809 | 0.78 | GRM8 (0.54) | GSRGRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL3678707 | 0.78 | GSR (0.54) | GSRGRM8GRM6GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854006-A | Gamma-glutamyl transpeptidase-specific antibody, prodrugs for the treatment of gamma-glutamyl transpeptidase-expressing tumors, and methods of administration thereof | THE UNIVERSITY OF VIRGINIA (US) | 1998-12-29 | — | — | US | disclosed |