Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18655732 | 0.86 | NQO1 (0.47) | NQO1TDP1TSHRMAPTMEN1 | |
| SCHEMBL12303239 | 0.82 | NQO1 (0.50) | NQO1TDP1TSHRLTA4HKDM4E | |
| SCHEMBL20411522 | 0.80 | CA12 (0.40) | TSHRMAPTMEN1KMT2AKDM4E | |
| SCHEMBL31680721 | 0.79 | NQO1 (0.46) | NQO1TDP1TSHRLTA4HMEN1 | |
| SCHEMBL19965680 | 0.77 | NQO1 (0.43) | NQO1TDP1TSHRLTA4HNPC1 | |
| SCHEMBL24244753 | 0.76 | MGLL (0.34) | MEN1KMT2A | |
| SCHEMBL14480364 | 0.75 | NQO1 (0.42) | NQO1TDP1TSHRLTA4HMAPT | |
| SCHEMBL14480252 | 0.75 | NQO1 (0.42) | NQO1TDP1TSHRLTA4HMAPT | |
| SCHEMBL24687082 | 0.74 | NQO1 (0.54) | NQO1TDP1TSHRLTA4HSYK | |
| SCHEMBL19231932 | 0.73 | MAPT (0.40) | NQO1TDP1TSHRMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023160672-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH LPA RECEPTOR ACTIVITY | LHOTSE BIO , INC. (US) | 2023-08-31 | — | — | WO | disclosed |