Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 3/20 | 0.46 |
| ▸ | FNTB | P49356 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23454485 | 0.81 | SPHK1 (0.48) | FNTAFNTBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL26436976 | 0.81 | SPHK1 (0.48) | FNTAFNTBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL3766063 | 0.77 | FNTA (0.50) | FNTAFNTBMAPTALDH1A1HTT | |
| SCHEMBL31075564 | 0.73 | FNTA (0.44) | FNTAFNTBMAPTALDH1A1HTT | |
| SCHEMBL7498532 | 0.73 | ALDH1A1 (0.73) | MAPTALDH1A1L3MBTL1 | |
| SCHEMBL25383961 | 0.72 | FNTA (0.46) | FNTAFNTBMAPTALDH1A1DNM1 | |
| SCHEMBL10847698 | 0.72 | FNTA (0.53) | FNTAFNTBMAPTALDH1A1DNM1 | |
| SCHEMBL17711572 | 0.71 | ALDH1A1 (0.70) | MAPTALDH1A1HTTL3MBTL1 | |
| SCHEMBL26205467 | 0.71 | FNTA (0.45) | FNTAFNTBMAPTALDH1A1HTT | |
| SCHEMBL6642732 | 0.71 | ALDH1A1 (0.76) | MAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164186-A1 | BENZOTHIA(DIA)ZEPINE COMPOUNDS FOR TREATMENT OF HBV AND HDV | ASSEMBLY BIOSCIENCES, INC. (US) | 2023-08-31 | — | — | WO | disclosed |
| WO-2023164186-A1 | BENZOTHIA(DIA)ZEPINE COMPOUNDS FOR TREATMENT OF HBV AND HDV | ASSEMBLY BIOSCIENCES, INC. (US) | 2023-08-31 | — | — | WO | disclosed |