Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17397067 | 0.87 | TDP1 (0.52) | KMT2AMEN1F7F3CYP2C19 | |
| Hydrochloric Acid SCHEMBL28280655 | 0.85 | CYP2C19 (0.50) | KMT2AMEN1F7F3CYP2C19 | |
| Acetic Acid SCHEMBL28542071 | 0.82 | TSHR (0.46) | KMT2AMEN1CYP2C19CYP3A4POLB | |
| SCHEMBL15758917 | 0.81 | F7 (0.61) | F7F3SARM1SIRT2SIRT6 | |
| Benzamide SCHEMBL27841146 | 0.77 | CYP3A4 (0.70) | KMT2AMEN1NPC1RAB9AF7 | |
| SCHEMBL21074576 | 0.74 | MKNK1 (0.67) | NPC1RAB9AF7F3SARM1 | |
| SCHEMBL21074472 | 0.74 | MKNK1 (0.67) | NPC1RAB9AF7F3SARM1 | |
| Benzoic Acid SCHEMBL3313836 | 0.73 | NAPRT (0.67) | KMT2AMEN1CYP2C19CYP3A4TSHR | |
| Benzophenone SCHEMBL4016306 | 0.73 | KMT2A (0.71) | KMT2AMEN1NPC1RAB9ACYP2C19 | |
| SCHEMBL7118621 | 0.73 | AKR1C1 (0.59) | KMT2AMEN1CYP2C19CYP3A4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3658552-B1 | PROCESS FOR PREPARING N-(5-((4-(4-((DIMETHYLAMINO)METHYL)-3-PHENYL-1H-PYRAZOL-1-YL)PYRIMIDIN-2-YL)AMINO)-4-METHOXY-2-MORPHOLINOPHENYL)ACRYLAMIDE BY REACTING THE CORRESPONDING AMINE WITH A 3-HALO-PROPIONYL CHLORIDE | YUHAN CORP (KR) | 2023-09-13 | — | — | EP | disclosed |
| CN-104788427-A | 3-(2-pyrimidine amino) phenyl acrylic amide compound and application thereof | PHARMARESOURCES SHANGHAI CO LTD | 2015-07-22 | — | — | CN | disclosed |
| CN-104788427-A | 3-(2-pyrimidine amino) phenyl acrylic amide compound and application thereof | PHARMARESOURCES SHANGHAI CO LTD | 2015-07-22 | — | — | CN | disclosed |