Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | DAO | P14920 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.61 |
| ▸ | APP | P05067 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.61 |
| ▸ | CES2 | O00748 | 2/20 | 0.56 |
| ▸ | CES1 | P23141 | 2/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.52 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | KMO | O15229 | 1/20 | 0.48 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.47 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.47 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL28647367 | 0.98 | NAPRT (0.64) | NAPRTTSHRDAOALDH1A1HCAR2 | |
| Benzoic Acid SCHEMBL27833807 | 0.98 | NAPRT (0.64) | NAPRTTSHRDAOALDH1A1HCAR2 | |
| Benzoic Acid SCHEMBL27846116 | 0.98 | NAPRT (0.64) | NAPRTTSHRDAOALDH1A1HCAR2 | |
| Benzoic Acid SCHEMBL27780742 | 0.90 | NAPRT (0.54) | NAPRTTSHRDAOALDH1A1HCAR2 | |
| Benzoic Acid SCHEMBL30336127 | 0.88 | NAPRT (0.52) | NAPRTTSHRDAOALDH1A1HCAR2 | |
| Benzoic Acid SCHEMBL28523082 | 0.88 | NAPRT (0.70) | NAPRTTSHRDAOALDH1A1HCAR2 | |
| Benzoic Acid SCHEMBL3811105 | 0.88 | NAPRT (0.70) | NAPRTTSHRDAOALDH1A1HCAR2 | |
| Benzoic Acid SCHEMBL28274408 | 0.88 | NAPRT (0.70) | NAPRTTSHRDAOALDH1A1HCAR2 | |
| Benzophenone SCHEMBL4016306 | 0.86 | KMT2A (0.71) | ALDH1A1HCAR2APPGAAHCAR3 | |
| Benzoic Acid SCHEMBL3847226 | 0.86 | NAPRT (0.67) | NAPRTTSHRDAOALDH1A1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119730951-A | Method for producing microparticles | 巴斯夫欧洲公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-114599644-B | Nicotinamide compound and herbicide composition containing the same | 韩国化学研究院 | 2024-08-02 | — | — | CN | disclosed |
| CN-114599644-A | Nicotinamide compound and herbicide composition containing the same | 韩国化学研究院 | 2022-06-07 | — | — | CN | disclosed |
| CN-110402924-A | Transplanted rice field super large age barnyard grass control method | HUAIAN CITY PLANT PROT AND INSPECTION STATION | 2019-11-05 | — | — | CN | disclosed |
| CN-109717196-A | A kind of Herbicidal combinations comprising penoxsuam, bispyribac-sodium and propanil | 佛山市盈辉作物科学有限公司 | 2019-05-07 | — | — | CN | disclosed |
| CN-106719733-A | A kind of rice field complex herbicidal composition | 浙江天丰生物科学有限公司 | 2017-05-31 | — | — | CN | disclosed |
| CN-103271063-B | Weeding composition | JIANGSU ROTAM CHEMISTRY CO LTD | 2015-05-27 | — | — | CN | disclosed |
| CN-102170780-B | Composition for improving the efficacy of herbicides | BASF SE | 2014-09-17 | — | — | CN | disclosed |
| CN-103271063-A | Weeding composition | JIANGSU ROTAM CHEMISTRY CO LTD | 2013-09-04 | — | — | CN | disclosed |
| CN-101151291-B | Polymer compositions and their use in the production of active or effective ingredient compositions | BASF AG | 2011-10-12 | — | — | CN | disclosed |
| US-20060030573-A1 | Substituted quinazolinone compounds | BOYCE RUSTUM S | 2006-02-09 | — | — | US | disclosed |
| EP-1551834-A1 | SUBSTITUTED QUINAZOLINONE COMPOUNDS | CHIRON CORPORATION (US) | 2005-07-13 | — | — | EP | disclosed |
| US-20050059662-A1 | Substituted quinazolinone compounds | CHIRON CORPORATION | 2005-03-17 | — | — | US | disclosed |
| WO-2004112793-A1 | GUANIDINO-SUBSTITUTED QUINAZOLINONE COMPOUNDS AS MC4-R AGONISTS | CHIRON CORPORATION (US) | 2004-12-29 | — | — | WO | disclosed |
| US-20040019049-A1 | Substituted quinazolinone compounds | CHIRON CORPORATION | 2004-01-29 | — | — | US | disclosed |
| WO-2003099818-A1 | SUBSTITUTED QUINAZOLINONE COMPOUNDS | CHIRON CORPORATION (US) | 2003-12-04 | — | — | WO | disclosed |
| US-5380460-A | Ferroelectric liquid crystal compounds containing chiral haloalkoxy tail units and compositions containing them | DISPLAYTECH, INC. (US) | 1995-01-10 | — | — | US | disclosed |
| EP-0589947-A1 | SULPHONAMIDE HERBICIDES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1994-04-06 | — | — | EP | disclosed |
| WO-1993006192-A1 | FERROELECTRIC LIQUID CRYSTAL COMPOUNDS CONTAINING CHIRAL HALOALKOXY TAIL UNITS AND COMPOSITIONS CONTAINING THEM | DISPLAYTECH, INCORPORATED (US) | 1993-04-01 | — | — | WO | disclosed |
| WO-1992022538-A1 | SULPHONAMIDE HERBICIDES | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1992-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050059662-A1 | Substituted quinazolinone compounds | MC4R, MC2R, MC3R | NAPRT 2255/4885TSHR 295/4885DAO 3959/4885 |
| US-20040019049-A1 | Substituted quinazolinone compounds | MC4R, MC2R, MC3R | NAPRT 2202/4885TSHR 250/4885DAO 3515/4885 |
| US-20060030573-A1 | Substituted quinazolinone compounds | MC4R, MC2R, MC3R | NAPRT 2184/4885TSHR 250/4885DAO 3381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.