Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | LIPE | Q05469 | 10/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25391320 | 1.00 | CACNA1B (0.47) | CACNA1BLIPEKCNA5PPARDFFAR4 | |
| SCHEMBL26978098 | 1.00 | CACNA1B (0.47) | CACNA1BLIPEKCNA5PPARDFFAR4 | |
| SCHEMBL25389457 | 1.00 | CACNA1B (0.47) | CACNA1BLIPEKCNA5PPARDFFAR4 | |
| SCHEMBL31288343 | 0.83 | LIPE (0.65) | CACNA1BLIPEKCNA5PPARDPDE5A | |
| SCHEMBL31288403 | 0.83 | LIPE (0.65) | CACNA1BLIPEKCNA5PPARDPDE5A | |
| SCHEMBL31288370 | 0.83 | LIPE (0.65) | CACNA1BLIPEKCNA5PPARDPDE5A | |
| SCHEMBL24227416 | 0.83 | LIPE (0.65) | CACNA1BLIPEKCNA5PPARDPDE5A | |
| SCHEMBL9104053 | 0.81 | KCNA5 (0.62) | KCNA5PPARDFFAR4CHRM4 | |
| SCHEMBL25390170 | 0.80 | HCRTR1 (0.47) | CHRM4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL25389384 | 0.80 | HCRTR1 (0.47) | CHRM4HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150186-A1 | DGK TARGETING COMPOUNDS AND USES THEREOF | ARVINAS OPERATIONS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |