Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | RBP4 | P02753 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KCNT1 | Q5JUK3 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25388421 | 1.00 | MAPT (0.50) | MAPTRBP4ALDH1A1LMNAKCNT1 | |
| SCHEMBL25391203 | 1.00 | MAPT (0.50) | MAPTRBP4ALDH1A1LMNAKCNT1 | |
| SCHEMBL25389728 | 1.00 | MAPT (0.50) | MAPTRBP4ALDH1A1LMNAKCNT1 | |
| SCHEMBL31282954 | 0.87 | MAPT (0.47) | MAPTALDH1A1KMT2AMAPK1MEN1 | |
| SCHEMBL31282832 | 0.87 | MAPT (0.47) | MAPTALDH1A1KMT2AMAPK1MEN1 | |
| SCHEMBL31282640 | 0.87 | MAPT (0.47) | MAPTALDH1A1KMT2AMAPK1MEN1 | |
| SCHEMBL25388905 | 0.87 | MAPT (0.47) | MAPTALDH1A1KMT2AMAPK1MEN1 | |
| SCHEMBL31288366 | 0.87 | MAPT (0.47) | MAPTALDH1A1KMT2AMAPK1MEN1 | |
| SCHEMBL25392633 | 0.86 | KMT2A (0.44) | MAPTALDH1A1LMNAKMT2AMAPK1 | |
| SCHEMBL25390910 | 0.86 | KMT2A (0.44) | MAPTALDH1A1LMNAKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150186-A1 | DGK TARGETING COMPOUNDS AND USES THEREOF | ARVINAS OPERATIONS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |