Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.69 |
| ▸ | SLC22A12 | Q96S37 | 9/20 | 0.53 |
| ▸ | EYA3 | Q99504 | 6/20 | 0.53 |
| ▸ | THRB | P10828 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | EYA2 | O00167 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.53 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALB | P02768 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30258722 | 0.89 | SLC22A12 (0.67) | TTRSLC22A12EYA3THRBCYP2C9 | |
| SCHEMBL25390573 | 0.88 | TTR (0.71) | TTRSLC22A12EYA3THRBCYP2C9 | |
| SCHEMBL25389911 | 0.88 | EYA3 (0.69) | TTREYA3THRBCYP2C9PTPN1 | |
| SCHEMBL25391104 | 0.88 | TTR (0.71) | TTRSLC22A12EYA3THRBCYP2C9 | |
| SCHEMBL25391064 | 0.87 | TTR (0.63) | TTRSLC22A12EYA3THRBCYP2C9 | |
| SCHEMBL25390412 | 0.83 | TTR (0.71) | TTRSLC22A12EYA3THRBCYP2C9 | |
| SCHEMBL1287644 | 0.82 | TTR (1.00) | TTRSLC22A12EYA3THRBCYP2C9 | |
| SCHEMBL25387610 | 0.80 | TTR (0.60) | TTRSLC22A12EYA3THRBCYP2C9 | |
| SCHEMBL25389953 | 0.79 | TTR (0.74) | TTRSLC22A12EYA3THRBCYP2C9 | |
| SCHEMBL25389800 | 0.79 | TTR (0.74) | TTRSLC22A12EYA3THRBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023149549-A1 | NOVEL PHARMACEUTICAL COMPOSITION | 国立大学法人富山大学 | 2023-08-10 | — | — | WO | disclosed |