Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 8/20 | 0.37 |
| ▸ | JAK1 | P23458 | 2/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25399736 | 0.95 | TYK2 (0.37) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| SCHEMBL25400339 | 0.95 | TYK2 (0.37) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| SCHEMBL25401077 | 0.84 | TYK2 (0.35) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| SCHEMBL25399309 | 0.82 | TYK2 (0.35) | TYK2 | |
| SCHEMBL25398442 | 0.82 | TYK2 (0.35) | TYK2 | |
| SCHEMBL25396660 | 0.77 | TYK2 (0.34) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| SCHEMBL25399521 | 0.77 | TYK2 (0.34) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| SCHEMBL25400069 | 0.76 | TYK2 (0.41) | TYK2 | |
| SCHEMBL25402457 | 0.72 | TYK2 (0.59) | TYK2 | |
| SCHEMBL25400945 | 0.67 | TYK2 (0.56) | TYK2JAK1JAK2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023169336-A1 | PYRIDAZINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | 成都科岭源医药技术有限公司 | 2023-09-14 | — | — | WO | disclosed |