Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 4/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25399309 | 1.00 | TYK2 (0.35) | TYK2CHRM1SMN1; SMN2HPGDNPSR1 | |
| SCHEMBL25396660 | 0.95 | TYK2 (0.34) | TYK2CHRM1SMN1; SMN2HPGDNPSR1 | |
| SCHEMBL25399521 | 0.95 | TYK2 (0.34) | TYK2CHRM1SMN1; SMN2HPGDNPSR1 | |
| SCHEMBL25400069 | 0.94 | TYK2 (0.41) | TYK2CHRM1SMN1; SMN2HPGDNPSR1 | |
| SCHEMBL25400810 | 0.85 | TYK2 (0.34) | TYK2 | |
| SCHEMBL25395884 | 0.82 | TYK2 (0.37) | TYK2 | |
| SCHEMBL25398581 | 0.81 | EGLN1 (0.32) | SMN1; SMN2 | |
| SCHEMBL25396541 | 0.80 | TUBB4A (0.32) | SMN1; SMN2NPSR1L3MBTL1 | |
| SCHEMBL25400219 | 0.79 | CACNA1H (0.30) | SMN1; SMN2 | |
| SCHEMBL25400339 | 0.77 | TYK2 (0.37) | TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023169336-A1 | PYRIDAZINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | 成都科岭源医药技术有限公司 | 2023-09-14 | — | — | WO | disclosed |