SCHEMBL2539764

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2536216	0.82	HRH3 (0.48)	HRH3KCNH2
	SCHEMBL2542622	0.81	PDE4A (0.54)	HRH3PDE4APDE4BPDE4CPDE4D
	SCHEMBL2536895	0.80	MEN1 (0.55)	HRH3
	SCHEMBL2536103	0.80	HRH3 (0.55)	HRH3KCNH2
	SCHEMBL2534940	0.79	HRH3 (0.46)	HRH3KCNH2
	SCHEMBL2534647	0.77	L3MBTL3 (0.52)	HRH3
	SCHEMBL2536227	0.75	HRH3 (0.48)	HRH3KCNH2
	SCHEMBL2542563	0.73	HRH3 (0.48)	HRH3KCNH2
	SCHEMBL2535575	0.73	HRH3 (0.46)	HRH3KCNH2
	SCHEMBL2535396	0.73	HRH3 (0.48)	HRH3KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.