Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 18/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25399745 | 0.93 | TYK2 (0.47) | TYK2ALDH1A1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL25398046 | 0.89 | TYK2 (0.55) | TYK2 | |
| SCHEMBL25401025 | 0.89 | TYK2 (0.64) | TYK2 | |
| SCHEMBL25395409 | 0.88 | TYK2 (0.53) | TYK2CYP2C19 | |
| SCHEMBL25397411 | 0.88 | TYK2 (0.53) | TYK2CYP2C19 | |
| SCHEMBL16794672 | 0.77 | TYK2 (0.46) | TYK2ALDH1A1 | |
| SCHEMBL24263411 | 0.71 | TYK2 (0.57) | TYK2 | |
| SCHEMBL25398581 | 0.71 | EGLN1 (0.32) | ALDH1A1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL16812530 | 0.71 | TYK2 (0.44) | TYK2ALDH1A1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL25400219 | 0.71 | CACNA1H (0.30) | ALDH1A1CYP1A2CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023169336-A1 | PYRIDAZINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | 成都科岭源医药技术有限公司 | 2023-09-14 | — | — | WO | disclosed |