Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25396541 | 0.93 | TUBB4A (0.32) | CACNA1HDRD1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL25400219 | 0.91 | CACNA1H (0.30) | CACNA1HALDH1A1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL25400810 | 0.90 | TYK2 (0.34) | — | |
| SCHEMBL25398442 | 0.81 | TYK2 (0.35) | SMN1; SMN2 | |
| SCHEMBL25400069 | 0.81 | TYK2 (0.41) | SMN1; SMN2 | |
| SCHEMBL25399309 | 0.81 | TYK2 (0.35) | SMN1; SMN2 | |
| SCHEMBL25396660 | 0.80 | TYK2 (0.34) | CYP2C19SMN1; SMN2 | |
| SCHEMBL25399521 | 0.80 | TYK2 (0.34) | CYP2C19SMN1; SMN2 | |
| SCHEMBL25398388 | 0.71 | TYK2 (0.49) | ALDH1A1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL25399069 | 0.68 | TUBB4A (0.43) | ALDH1A1CYP1A2CYP2C19SMN1; SMN2PDE1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023169336-A1 | PYRIDAZINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | 成都科岭源医药技术有限公司 | 2023-09-14 | — | — | WO | disclosed |