Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 8/20 | 0.59 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.59 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.50 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.43 |
| ▸ | SCN4A | P35499 | 1/20 | 0.43 |
| ▸ | PARP14 | Q460N5 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.41 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.41 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3692809 | 0.83 | PARP10 (0.61) | PARP10PARP3PARP15SCN9ASCN4A | |
| SCHEMBL28260959 | 0.83 | PARP10 (0.56) | PARP10PARP15DGAT1SCN9APARP14 | |
| SCHEMBL15653294 | 0.82 | DGAT1 (0.56) | PARP10PARP3PARP15DGAT1PARP14 | |
| SCHEMBL1874234 | 0.80 | PARP10 (0.50) | PARP10PARP3PARP15SCN9ASCN4A | |
| SCHEMBL4238777 | 0.80 | PARP10 (0.50) | PARP10PARP15DGAT1SCN9APARP14 | |
| SCHEMBL31238504 | 0.79 | SOS1 (0.54) | PARP10PARP3KMT2AALDH1A1POLB | |
| SCHEMBL4853836 | 0.79 | SOS1 (0.54) | PARP10PARP3KMT2AALDH1A1POLB | |
| SCHEMBL3691759 | 0.77 | PARP10 (0.51) | PARP10PARP15DGAT1PARP14KMT2A | |
| SCHEMBL1874719 | 0.77 | PARP10 (0.54) | PARP10PARP3PARP15PARP14KMT2A | |
| SCHEMBL3696878 | 0.77 | PARP10 (0.53) | PARP10PARP3PARP15SCN9ASCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4489748-A1 | PURE FORMS OF CRYSTALLINE ATICAPRANT | Janssen Pharmaceuticals, Inc. (US) | 2025-01-15 | — | — | EP | disclosed |
| WO-2023170547-A1 | PURE FORMS OF CRYSTALLINE ATICAPRANT | Janssen Pharmaceuticals, Inc. (US) | 2023-09-14 | — | — | WO | disclosed |