Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 4/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | CA9 | Q16790 | 3/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1317499 | 0.89 | LPL (0.43) | LPLLIPGESR2TRPV4ROCK1 | |
| SCHEMBL4219113 | 0.82 | LPL (0.38) | LPLLIPGESR2TRPV4ROCK1 | |
| SCHEMBL16534950 | 0.82 | LPL (0.38) | LPLLIPGESR2TRPV4ROCK1 | |
| SCHEMBL27198578 | 0.79 | LPL (0.36) | LPLLIPGESR2TRPV4ROCK1 | |
| SCHEMBL20253387 | 0.79 | LPL (0.36) | LPLLIPGESR2TRPV4ROCK1 | |
| SCHEMBL30827381 | 0.79 | LPL (0.36) | LPLLIPGESR2TRPV4ROCK1 | |
| SCHEMBL16655624 | 0.79 | LPL (0.43) | LPLLIPGESR2ROCK1CA1 | |
| SCHEMBL27087945 | 0.78 | LPL (0.42) | LPLLIPGROCK1CA1CA2 | |
| SCHEMBL29867623 | 0.78 | LPL (0.42) | LPLLIPGROCK1CA1CA2 | |
| SCHEMBL30673379 | 0.77 | LPL (0.39) | LPLLIPGROCK1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023155886-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-08-24 | — | — | WO | disclosed |