Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | USP14 | P54578 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 2/20 | 0.34 |
| ▸ | KIT | P10721 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25401435 | 0.82 | PDE3B (0.39) | PDE3BPDE3AP2RY12APPALDH1A1 | |
| SCHEMBL25400142 | 0.81 | ALDH1A1 (0.35) | GRM2ALDH1A1F2GLAHPGD | |
| Acetic Acid SCHEMBL25400146 | 0.79 | GAA (0.45) | ALDH1A1F2HPGD | |
| SCHEMBL25401317 | 0.78 | MAOB (0.47) | ALDH1A1F2GLAHPGDMAOB | |
| SCHEMBL20719579 | 0.78 | ACACB (0.43) | GRM2ALDH1A1USP14PDE4BKDM1A | |
| SCHEMBL30554488 | 0.78 | ACACB (0.43) | GRM2ALDH1A1USP14PDE4BKDM1A | |
| SCHEMBL9519051 | 0.77 | MYC (0.40) | PDE3BPDE3AP2RY12APPGRM2 | |
| SCHEMBL30570055 | 0.77 | GAA (0.48) | ALDH1A1HPGD | |
| SCHEMBL20809627 | 0.70 | TP53 (0.47) | ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL17316360 | 0.70 | KDM1A (0.50) | ALDH1A1USP14KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023169554-A1 | METHIONINE ADENOSINE TRANSFERASE INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 赛诺哈勃药业（成都）有限公司 | 2023-09-14 | — | — | WO | disclosed |