Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.33 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1449735 | 0.83 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1SMN1; SMN2GAAMAPT | |
| SCHEMBL1449733 | 0.83 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1SMN1; SMN2GAAMAPT | |
| SCHEMBL1094509 | 0.76 | PDPK1 (0.34) | ALDH1A1SMN1; SMN2PDE4APDE4BPDE4C | |
| SCHEMBL29253838 | 0.76 | L3MBTL1 (0.38) | L3MBTL1ALDH1A1SMN1; SMN2GAAMAP3K7 | |
| SCHEMBL23326490 | 0.75 | L3MBTL1 (0.42) | L3MBTL1ALDH1A1SMN1; SMN2GAAKDM4E | |
| SCHEMBL19422501 | 0.73 | PDPK1 (0.34) | — | |
| SCHEMBL13949410 | 0.73 | PDPK1 (0.34) | — | |
| SCHEMBL11913126 | 0.70 | CA12 (0.43) | ALDH1A1SMN1; SMN2GAAMAPTMAP3K7 | |
| SCHEMBL1440229 | 0.66 | PDPK1 (0.37) | ALDH1A1SMN1; SMN2PDE4APDE4BPDE4C | |
| SCHEMBL14782611 | 0.66 | PDPK1 (0.39) | L3MBTL1ALDH1A1SMN1; SMN2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023178130-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2023-09-21 | — | — | WO | disclosed |