Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2525193 | 1.00 | MAPT (0.46) | MAPTKMT2AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL2101375 | 0.81 | USP2 (0.40) | MAPTKMT2ASMN1; SMN2USP2CTSK | |
| SCHEMBL10374140 | 0.80 | MAPT (0.50) | MAPTKMT2AALDH1A1CYP1A2CYP2C19 | |
| Oxygen SCHEMBL28667256 | 0.79 | USP2 (0.39) | MAPTKMT2ASMN1; SMN2USP2CTSK | |
| SCHEMBL16416175 | 0.78 | USP2 (0.38) | MAPTSMN1; SMN2USP2CTSKKDM1A | |
| SCHEMBL229110 | 0.77 | KMT2A (0.50) | MAPTKMT2AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL3243997 | 0.76 | USP2 (0.44) | MAPTKMT2AALDH1A1SMN1; SMN2USP2 | |
| SCHEMBL20304663 | 0.74 | NR1H2 (0.37) | SMN1; SMN2USP2CTSKKDM1ANR1H2 | |
| SCHEMBL823726 | 0.74 | — | — | |
| SCHEMBL3255385 | 0.73 | CTSK (0.49) | MAPTKMT2AALDH1A1SMN1; SMN2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039501-B2 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2011-10-18 | — | — | US | disclosed |