Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 17/20 | 0.51 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | IKBKB | O14920 | 5/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30899087 | 0.79 | LRRK2 (0.47) | CHUKLRRK2 | |
| SCHEMBL28274262 | 0.79 | LRRK2 (0.47) | CHUKLRRK2 | |
| SCHEMBL31586107 | 0.79 | LRRK2 (0.47) | CHUKLRRK2 | |
| SCHEMBL26638109 | 0.76 | LRRK2 (0.44) | CHUKLRRK2 | |
| SCHEMBL5260963 | 0.75 | LRRK2 (0.54) | CHUKLRRK2 | |
| SCHEMBL30199352 | 0.75 | LRRK2 (0.54) | CHUKLRRK2 | |
| SCHEMBL25158173 | 0.74 | AXL (0.48) | — | |
| SCHEMBL3827956 | 0.74 | LRRK2 (0.53) | CHUKLRRK2IKBKB | |
| Hydrochloric Acid SCHEMBL28274256 | 0.74 | LRRK2 (0.53) | CHUKLRRK2 | |
| SCHEMBL17769864 | 0.73 | MAP3K14 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023177351-A1 | NF ҚB INDUCING KINASE INHIBITORS AND METHODS THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2023-09-21 | — | — | WO | disclosed |