⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17392981 | 1.00 | — | — | |
| SCHEMBL26095297 | 1.00 | — | — | |
| SCHEMBL283035 | 0.79 | — | — | |
| SCHEMBL283034 | 0.79 | — | — | |
| SCHEMBL429455 | 0.79 | — | — | |
| Methane SCHEMBL28591036 | 0.77 | — | — | |
| SCHEMBL487100 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL29133641 | 0.75 | — | — | |
| SCHEMBL8182891 | 0.75 | — | — | |
| SCHEMBL30242100 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4650353-A1 | 4-ALKOXY BENZIMIDAZOLE-6-CARBOXYLIC ACID DERIVATIVE SERVING AS GLP-1 RECEPTOR AGONIST | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2025-11-19 | — | — | EP | disclosed |
| WO-2025021048-A1 | POLYCYCLIC COMPOUND AND USE THEREOF | 石药集团中奇制药技术（石家庄）有限公司 | 2025-01-30 | — | — | WO | disclosed |
| WO-2024149080-A1 | 4-ALKOXY BENZIMIDAZOLE-6-CARBOXYLIC ACID DERIVATIVE SERVING AS GLP-1 RECEPTOR AGONIST | 中国科学院上海药物研究所 | 2024-07-18 | — | — | WO | disclosed |
| CN-118344349-A | 4-Alkoxybenzimidazole-6-carboxylic acid derivatives as GLP-1 receptor agonists | 中国科学院上海药物研究所 | 2024-07-16 | — | — | CN | disclosed |
| CN-118271300-A | Lactam compound, and preparation method and application thereof | 广州市联瑞制药有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-118271299-A | Lactam compound, and preparation method and application thereof | 广州市联瑞制药有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-113493447-B | GLP-1 receptor agonists | 轩竹(北京)医药科技有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-118084936-A | Three-ring-containing compound and application thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-117903088-A | Preparation method of (S) -oxetane-2-methylamine | 南京药石科技股份有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-117903088-A | Preparation method of (S) -oxetane-2-methylamine | 南京药石科技股份有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-116217522-A | Chiral purification method of key intermediate of GLP-1 receptor agonist | 广东莱佛士制药技术有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-116102543-A | GLP-1R agonist, synthesis method and application thereof | 江南大学 | 2023-05-12 | — | — | CN | disclosed |
| CN-116082321-A | Imidazo-aryl derivative, pharmaceutical composition and application thereof | 华中药业股份有限公司 | 2023-05-09 | — | — | CN | disclosed |
| WO-2023066356-A1 | COMPOUND AS GLP-1 RECEPTOR AGONIST AND USE THEREOF | 盛世泰科生物医药技术(苏州)有限公司 | 2023-04-27 | — | — | WO | disclosed |
| WO-2023065434-A1 | PREPARATION METHOD FOR OXETANE-2-METHYLAMINE | 韶远科技（上海)有限公司 | 2023-04-27 | — | — | WO | disclosed |
| CN-116003393-A | Compounds as GLP-1 receptor agonists and uses thereof | 盛世泰科生物医药技术(苏州)有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-115991685-A | Preparation method of oxetane-2-methylamine | 韶远科技（上海)有限公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-115521297-A | 5,6-dihydro-1,2,4-triazines and their pharmaceutical use as GLP-1 receptor agonists | 中国科学院上海药物研究所 | 2022-12-27 | — | — | CN | disclosed |
| WO-2022228490-A1 | POLYCYCLIC DERIVATIVE MODULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2022-11-03 | — | — | WO | disclosed |
| CN-114716423-A | 5, 6-dihydro-1, 2, 4-triazines and their pharmaceutical use as GLP-1 receptor agonists | 中国科学院上海药物研究所 | 2022-07-08 | — | — | CN | disclosed |