⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL429455 | 1.00 | — | — | |
| SCHEMBL283034 | 1.00 | — | — | |
| Methane SCHEMBL28591036 | 0.97 | — | — | |
| SCHEMBL487100 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL29133641 | 0.90 | — | — | |
| SCHEMBL8182891 | 0.90 | — | — | |
| SCHEMBL25401428 | 0.79 | — | — | |
| SCHEMBL26095297 | 0.79 | — | — | |
| SCHEMBL17392981 | 0.79 | — | — | |
| SCHEMBL10340288 | 0.77 | NOS2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 283 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110981838-B | 5-imine-tetrahydrofuryl methylamine derivative and preparation method and application thereof | 中国人民解放军第四军医大学 | 2023-03-24 | — | — | CN | claimed |
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | claimed |
| US-8202876-B2 | Compounds and compositions as protein kinase inhibitors | IRM LLC (BM) | 2012-06-19 | — | — | US | claimed |
| US-20100029605-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2010-02-04 | — | — | US | claimed |
| EP-2057146-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2009-05-13 | — | — | EP | claimed |
| WO-2008042639-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2008-04-10 | — | — | WO | claimed |
| CN-114072393-B | 3-Amino-4H-benzo [ E ] [1,2,4] thiadiazine 1, 1-dioxide derivatives as MRGX2 inhibitors | 索伦特治疗有限责任公司 | 2025-05-27 | — | — | CN | disclosed |
| CN-113226356-B | Activation of pyruvate kinase R | 诺沃挪第克健康护理股份公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-119504587-A | Indenoazepine compound, preparation method and medical application thereof | 贵州民族大学 | 2025-02-25 | — | — | CN | disclosed |
| CN-116234552-B | Dual modulators of mGluR5 and 5-HT2A receptors and uses thereof | (株)倍宝尊 | 2025-02-25 | — | — | CN | disclosed |
| CN-118891039-A | Selective G protein coupled receptor kinase 5 inhibitors, compositions and methods of use | 普渡研究基金会 | 2024-11-01 | — | — | CN | disclosed |
| CN-115745960-B | Compound containing quinolinone amide, preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2024-08-30 | — | — | CN | disclosed |
| CN-118414337-A | Pyrazolopyrimidine derivative and anticancer pharmaceutical composition containing same as active ingredient | 韩国化学研究院 | 2024-07-30 | — | — | CN | disclosed |
| EP-0801083-A2 | Improved functionalized resin for chemical synthesis | PFIZER INC. (US) | 1997-10-15 | — | — | EP | disclosed |
| WO-1997023508-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-07-03 | — | — | WO | disclosed |
| EP-0158922-A2 | Tetrahydrofuran-2-ylmethylamines | BAYER AG (DE) | 1985-10-23 | — | — | EP | disclosed |
| US-4491671-A | Process for the preparation of N-substituted imido-dicarboxylic acid diaryl esters | BAYER AKTIENGESELLSCHAFT (DE) | 1985-01-01 | — | — | US | disclosed |
| US-4348331-A | FROM THE HYDROCHLORIDE OF A PRIMARY AMINE AND AN ARYL ESTER HALIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1982-09-07 | — | — | US | disclosed |
| US-4210648-A | ANTIULCEROGENICS, SECRETION INHIBITORS | BOEHRINGER INGELHEIM GMBH (DE) | 1980-07-01 | — | — | US | disclosed |
| US-4210648-A | ANTIULCEROGENICS, SECRETION INHIBITORS | BOEHRINGER INGELHEIM GMBH (DE) | 1980-07-01 | — | — | US | disclosed |