SCHEMBL25403

SCHEMBL25403

COC[C](C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1926176 0.75
SCHEMBL5498275 0.73
SCHEMBL1926197 0.72
SCHEMBL1298690 0.72
SCHEMBL6437786 0.72
SCHEMBL1495207 0.70
SCHEMBL7022197 0.70
SCHEMBL23959171 0.69
SCHEMBL13130705 0.69
SCHEMBL10045848 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 954 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024115549-A1 ARYL- AND HETEROARYL-SULFONAMIDE DERIVATIVES AS CCR8 MODULATORS IDORSIA PHARMACEUTICALS LTD (CH) 2024-06-06 WO claimed
CN-116751200-A Tricyclic compounds containing substituted pyridones and methods of using the same 爱彼特生物制药公司 2023-09-15 CN claimed
EP-3766882-B1 PHTHALAZINE ISOXAZOLE ALKOXY DERIVATIVES, PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION AND USE THEREOF SHANGHAI SIMR BIOTECHNOLOGY CO LTD (CN) 2023-08-23 EP claimed
CN-116554109-A Inhibitors of bruton's tyrosine kinase and methods of preparing the same 中山大学 2023-08-08 CN claimed
US-20230219965-A1 NITROGEN-CONTAINING FUSED BICYCLIC COMPOUNDS AND THEIR USE AS UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 1 (USP1) INHIBITORS KSQ Therapeutics, Inc. 2023-07-13 US claimed
CN-110114071-B Tricyclic compounds containing substituted pyridones and methods of using the same 爱彼特生物制药公司 2023-07-04 CN claimed
EP-4161494-A1 NITROGEN-CONTAINING FUSED BICYCLIC COMPOUNDS AND THEIR USE AS UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 1 (USP1) INHIBITORS KSQ Therapeutics, Inc. (US) 2023-04-12 EP claimed
CN-114933556-A Preparation method of thioether compound 苏州照固新材料科技有限公司 2022-08-23 CN claimed
CN-111217736-B Method for synthesizing 2-acylindole compound under photocatalysis 陕西科技大学 2021-07-02 CN claimed
US-11013726-B2 Substituted pyridinone-containing trycyclic compounds, and methods using same ARBUTUS BIOPHARMA CORPORATION (CA) 2021-05-25 US claimed
EP-0329360-A2 Pyridine derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-08-23 EP claimed
EP-0074511-B1 2H-1,2,4,6-THIATRIAZIN(3)ON-1,1 DIOXIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES BASF Aktiengesellschaft (DE) 1987-12-09 EP claimed
US-4675280-A LIGHTFAST AND FORMACIN RESISTANT KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1987-06-23 US claimed
US-4665015-A LIGHT FAST DYE IMAGE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1987-05-12 US claimed
EP-0178788-A1 Silver halide color photographic material KONICA CORPORATION (JP) 1986-04-23 EP claimed
EP-0178166-A1 Silver halide color photographic material KONICA CORPORATION (JP) 1986-04-16 EP claimed
EP-0078462-B1 1,2,4,6-THIATRIAZINE-1,1 DIOXIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTI-GROWTH AGENTS FOR UNWANTED PLANTS BASF Aktiengesellschaft (DE) 1986-01-15 EP claimed
EP-0033088-B1 ANTIMYCOTIC AGENTS BAYER AG (DE) 1983-05-25 EP claimed
US-4316015-A 6H-1,2,4,6-Thiatriazine-1,1-dioxides BASF AKTIENGESELLSCHAFT (DE) 1982-02-16 US claimed
EP-0033088-A2 Antimycotic agents BAYER AG (DE) 1981-08-05 EP claimed