Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 12/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 10/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 10/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | CDK9 | P50750 | 2/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25158173 | 0.78 | AXL (0.48) | CLK1CDK5CDK5R1MAPK1ALDH1A1 | |
| SCHEMBL17769864 | 0.77 | MAP3K14 (0.38) | CLK1CDK5CDK5R1ALDH1A1CCNT1 | |
| SCHEMBL12120921 | 0.77 | TYRO3 (0.42) | MAPK1CHEK1BRD4 | |
| SCHEMBL30475606 | 0.77 | TYRO3 (0.42) | MAPK1CHEK1BRD4 | |
| SCHEMBL13219255 | 0.73 | MAPK1 (0.38) | CLK1CDK5CDK5R1MAPK1CHEK1 | |
| SCHEMBL25401085 | 0.73 | CHUK (0.51) | — | |
| SCHEMBL311676 | 0.72 | RPS6KA5 (0.45) | CLK1CDK5MAPK1CHEK1CDK2 | |
| SCHEMBL23451864 | 0.72 | CDK2 (0.53) | CLK1CDK5CCNT1CCNA2CDK2 | |
| SCHEMBL4697304 | 0.69 | RET (0.41) | ALDH1A1CDK2PDPK1CYP3A4 | |
| SCHEMBL30822335 | 0.69 | RET (0.41) | ALDH1A1CDK2PDPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023177351-A1 | NF ҚB INDUCING KINASE INHIBITORS AND METHODS THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2023-09-21 | — | — | WO | disclosed |