Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.44 |
| ▸ | F13A1 | P00488 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | TGM1 | P22735 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27039596 | 0.91 | MEN1 (0.46) | MEN1KMT2ANPY2RGPR119F13A1 | |
| SCHEMBL25404474 | 0.90 | MEN1 (0.45) | MEN1KMT2ANPY2RGPR119F13A1 | |
| SCHEMBL29157847 | 0.87 | NPY2R (0.48) | NPY2RGPR119MAPTNAMPTACHE | |
| SCHEMBL25404333 | 0.84 | GPR119 (0.48) | MEN1KMT2AGPR119F13A1TGM2 | |
| SCHEMBL25404825 | 0.84 | GPR119 (0.48) | MEN1KMT2AGPR119F13A1TGM2 | |
| SCHEMBL25402776 | 0.83 | MEN1 (0.43) | MEN1KMT2ANPY2RGPR119F13A1 | |
| SCHEMBL30830549 | 0.83 | GPR119 (0.53) | MEN1KMT2AGPR119MAPTSMN1; SMN2 | |
| SCHEMBL14982163 | 0.81 | MEN1 (0.50) | MEN1KMT2ANPY2RGPR119F13A1 | |
| SCHEMBL22119644 | 0.80 | DDB1 (0.56) | MEN1KMT2AGPR119MAPTTSHR | |
| SCHEMBL30703631 | 0.80 | MAPT (0.46) | MEN1KMT2ANPY2RGPR119F13A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118742539-A | Heterocyclic derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2024-10-01 | — | — | CN | disclosed |
| WO-2023169391-A1 | HETEROCYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江海正药业股份有限公司 | 2023-09-14 | — | — | WO | disclosed |