Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | TP53 | P04637 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | RAF1 | P04049 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TYK2 | P29597 | 2/20 | 0.54 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.52 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | RIOK2 | Q9BVS4 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25404170 | 0.89 | TP53 (0.64) | ALDH1A1TP53POLBKDM4EMAPT | |
| SCHEMBL25407042 | 0.89 | TP53 (0.65) | ALDH1A1TP53POLBKDM4EMAPT | |
| SCHEMBL25403054 | 0.85 | TP53 (0.62) | TP53POLBKDM4EMAPTRAF1 | |
| SCHEMBL25406341 | 0.84 | KDM4E (0.67) | ALDH1A1TP53POLBKDM4EMAPT | |
| SCHEMBL25402398 | 0.81 | F2 (0.59) | ALDH1A1TP53MAPTLMNAMEN1 | |
| SCHEMBL25405780 | 0.80 | MEN1 (0.65) | ALDH1A1TP53POLBMAPTLMNA | |
| SCHEMBL5638178 | 0.80 | SMN1; SMN2 (0.79) | ALDH1A1TP53POLBKDM4EMAPT | |
| SCHEMBL25404462 | 0.79 | CHEK1 (0.56) | TP53POLBKDM4EMAPTTYK2 | |
| SCHEMBL25189182 | 0.79 | RIOK2 (0.60) | ALDH1A1TP53KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL3932265 | 0.79 | RIOK2 (0.57) | ALDH1A1TP53SMN1; SMN2RIOK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023176554-A1 | COGNITIVE-FUNCTION-IMPROVING AGENT | 国立大学法人東北大学 | 2023-09-21 | — | — | WO | claimed |
| WO-2023176554-A1 | COGNITIVE-FUNCTION-IMPROVING AGENT | 国立大学法人東北大学 | 2023-09-21 | — | — | WO | disclosed |