Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | RIOK2 | Q9BVS4 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | GCK | P35557 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.57 |
| ▸ | GSK3A | P49840 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | XBP1 | P17861 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | CLK2 | P49760 | 1/20 | 0.53 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.53 |
| ▸ | NEK4 | P51957 | 1/20 | 0.53 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25402398 | 0.91 | F2 (0.59) | TP53RIOK2GCKMAPK10GSK3A | |
| SCHEMBL25407042 | 0.89 | TP53 (0.65) | TP53RIOK2KDM4EGCKPOLB | |
| SCHEMBL25405258 | 0.89 | ALDH1A1 (0.66) | TP53RIOK2KDM4EPOLBALDH1A1 | |
| SCHEMBL3932265 | 0.88 | RIOK2 (0.57) | TP53RIOK2GCKMAPK10GSK3A | |
| SCHEMBL25189182 | 0.88 | RIOK2 (0.60) | TP53RIOK2KDM4EGCKMAPK10 | |
| SCHEMBL25406525 | 0.87 | KDR (0.71) | TP53RIOK2MAPK10GSK3AALDH1A1 | |
| SCHEMBL25402019 | 0.86 | NR3C2 (0.67) | TP53RIOK2GCKMAPK10GSK3A | |
| SCHEMBL25404689 | 0.86 | TP53 (0.61) | TP53RIOK2KDM4EMAPK10GSK3A | |
| SCHEMBL25404025 | 0.86 | NPC1 (0.53) | TP53RIOK2GCKMAPK10GSK3A | |
| SCHEMBL25404715 | 0.86 | SMN1; SMN2 (0.66) | TP53POLBNPC1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023176554-A1 | COGNITIVE-FUNCTION-IMPROVING AGENT | 国立大学法人東北大学 | 2023-09-21 | — | — | WO | disclosed |
| WO-2023176554-A1 | COGNITIVE-FUNCTION-IMPROVING AGENT | 国立大学法人東北大学 | 2023-09-21 | — | — | WO | disclosed |