Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.37 |
| ▸ | DUT | P33316 | 9/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.32 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.32 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.32 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25701041 | 0.89 | PKM (0.42) | POLBHSD17B10PKMCRBNDUT | |
| SCHEMBL21318352 | 0.85 | PKM (0.43) | POLBHSD17B10PKMALDH1A1LMNA | |
| SCHEMBL14389711 | 0.81 | PKM (0.43) | POLBHSD17B10PKMALDH1A1LMNA | |
| SCHEMBL11102286 | 0.81 | PKM (0.43) | POLBHSD17B10PKMALDH1A1LMNA | |
| SCHEMBL25611388 | 0.80 | POLB (0.61) | POLBHSD17B10PKMALDH1A1LMNA | |
| SCHEMBL21935625 | 0.80 | POLB (0.67) | POLBHSD17B10PKMALDH1A1LMNA | |
| SCHEMBL25605484 | 0.79 | POLB (0.55) | POLBHSD17B10PKMALDH1A1LMNA | |
| SCHEMBL25605487 | 0.79 | POLB (0.55) | POLBHSD17B10PKMALDH1A1LMNA | |
| SCHEMBL15216128 | 0.78 | PKM (0.39) | POLBHSD17B10PKMALDH1A1LMNA | |
| SCHEMBL16579294 | 0.78 | POLB (0.41) | POLBHSD17B10PKMALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014127378-A2 | DESIGN OF SHORT OLIGONUCLEOTIDES AS VACCINE ADJUVANTS AND THERAPEUTIC AGENTS | SPRING BANK PHARMACEUTICALS, INC. (US) | 2014-08-21 | — | — | WO | disclosed |
| WO-2012030626-A2 | DESIGN OF OLIGONUCLEOTIDE ANALOGS AS THERAPEUTIC AGENTS | SPRING BANK PHARMACEUTICALS, INC. (US) | 2012-03-08 | — | — | WO | disclosed |