Salacetamide

Salacetamide

SCHEMBL25410

CC(=O)NC(=O)c1ccccc1O

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.61
GAA P10253 3/20 0.61
SMN1; SMN2 Q16637 3/20 0.61
MPO P05164 1/20 0.61
HIF1A Q16665 1/20 0.61
LMNA P02545 7/20 0.55
NPC1 O15118 5/20 0.55
HTT P42858 4/20 0.55
HPGD P15428 4/20 0.55
HSD17B10 Q99714 4/20 0.55
TP53 P04637 3/20 0.55
KMT2A Q03164 3/20 0.55
MEN1 O00255 2/20 0.55
TSHR P16473 1/20 0.53
RAB9A P51151 4/20 0.53
ALDH1A1 P00352 4/20 0.53
MAPT P10636 2/20 0.53
MAPK1 P28482 1/20 0.53
USP2 O75604 1/20 0.53
NFKB1 P19838 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Salacetamide SCHEMBL6696816 0.93 KDM4E (0.53) KDM4EGAASMN1; SMN2MPOHIF1A
SCHEMBL70688 0.87 KDM4E (0.71) KDM4EGAASMN1; SMN2MPOHIF1A
Salacetamide SCHEMBL29288268 0.85 CA1 (0.52) KDM4EGAASMN1; SMN2MPOHIF1A
SCHEMBL29851354 0.82 CA1 (0.65) KDM4EGAASMN1; SMN2MPOHIF1A
SCHEMBL1169719 0.82 CA1 (0.65) KDM4EGAASMN1; SMN2MPOHIF1A
SCHEMBL6994934 0.81 KDM4E (0.63) KDM4EGAASMN1; SMN2MPOHIF1A
SCHEMBL10904872 0.81 KDM4E (0.63) KDM4EGAASMN1; SMN2MPOHIF1A
SCHEMBL29191662 0.79 SMN1; SMN2 (0.62) KDM4ESMN1; SMN2LMNANPC1HTT
SCHEMBL1563698 0.79 GAA (0.67) KDM4EGAASMN1; SMN2MPOHIF1A
SCHEMBL1799299 0.78 KDM4E (0.65) KDM4EGAASMN1; SMN2MPOHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2886 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4352178-A1 THERMALLY CURABLE HOT-MELT PRESSURE SENSITIVE ADHESIVE BASF SE (DE) 2024-04-17 EP claimed
US-20240041935-A1 PREVENTION AND TREATMENT OF REPRODUCTIVE FAILURE BY REGENERATIVE CELLS AND ADJUVANTS CREATIVE MEDICAL TECHNOLOGIES, INC. (US) 2024-02-08 US claimed
WO-2022261123-A1 THERMALLY CURABLE HOT-MELT PRESSURE SENSITIVE ADHESIVE BASF SE (DE) 2022-12-15 WO claimed
US-20210145763-A1 LOW THC HEMP EXTRACT AND METHOD OF TREATMENT OR PREVENTION OF AN EYE DISEASE EYE CO PTY LTD. (AU) 2021-05-20 US claimed
EP-3773651-A1 LOW THC HEMP EXTRACT AND METHOD OF TREATMENT OR PREVENTION OF AN EYE DISEASE Eye Co Pty Ltd. (AU) 2021-02-17 EP claimed
WO-2019191800-A1 LOW THC HEMP EXTRACT AND METHOD OF TREATMENT OR PREVENTION OF AN EYE DISEASE EYE CO PTY LTD (AU) 2019-10-10 WO claimed
US-20190136453-A1 FLUFF PULP AND HIGH SAP LOADED CORE ALLY BANK, AS COLLATERAL AGENT 2019-05-09 US claimed
US-20180071710-A1 Magnetic Adsorbent for Removing Arsenic and Antimony by means of Adsorption-Superconducting Magnetic Separation and Preparation Method therefor RESEARCH CENTER FOR ECO-ENVIRONMENTAL SCIENCES, CHINESE ACADEMY OF SCIENCES (CN) 2018-03-15 US claimed
US-20170283606-A1 WATER-IN-OIL POLYACRYLAMIDE-BASED MICROEMULSIONS AND RELATED METHODS EXACTO, LLC 2017-10-05 US claimed
US-9283188-B2 Delivery systems for delivering functional compounds to substrates and processes of using the same KIMBERLY-CLARK WORLDWIDE, INC. (US) 2016-03-15 US claimed
WO-1998020864-A2 USE OF SELECTED NON-STEROIDAL ANTIINFLAMMATORY COMPOUNDS FOR THE PREVENTION AND THE TREATMENT OF NEURODEGENERATIVE DISEASES UNIVERSITA' DEGLI STUDI DI BRESCIA - DIPARTIMENTO DI SCIENZE BIOMEDICHE (IT) 1998-05-22 WO claimed
EP-0792371-A1 COMBINATION METHOD FOR ACNE TREATMENT Merck & Co., Inc. (US) 1997-09-03 EP claimed
EP-0786999-A1 COMBINATION METHOD FOR ACNE TREATMENT Merck & Co., Inc. (US) 1997-08-06 EP claimed
US-5543417-A 5 Alpha-reductase inhibitor and at least one of an antibacterial agent, a keratolytic agent or an anti-inflammatory agent MERCK & CO., INC. (US) 1996-08-06 US claimed
WO-1996012487-A1 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO., INC. (US) 1996-05-02 WO claimed
WO-1996012817-A1 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO., INC. (US) 1996-05-02 WO claimed
EP-0482838-B1 Transparent liquid absorbent materials for use as ink-receptive layers MINNESOTA MINING & MFG (US) 1995-03-08 EP claimed
EP-0482838-A1 Transparent liquid absorbent materials for use as ink-receptive layers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-04-29 EP claimed
EP-0046270-B1 NOVEL DERIVATIVES OF BIO-AFFECTING PHENOLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITION CONTAINING THEM INTERx RESEARCH CORPORATION (US) 1986-05-21 EP claimed
EP-0046270-A1 Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them INTERx RESEARCH CORPORATION (US) 1982-02-24 EP claimed