SCHEMBL1799299

SCHEMBL1799299

CNC(=O)c1ccccc1O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.65
GAA P10253 3/20 0.65
SMN1; SMN2 Q16637 3/20 0.65
MPO P05164 1/20 0.65
HIF1A Q16665 1/20 0.65
LMNA P02545 7/20 0.59
HPGD P15428 6/20 0.59
HSD17B10 Q99714 5/20 0.59
HTT P42858 4/20 0.59
TP53 P04637 3/20 0.59
MEN1 O00255 3/20 0.59
KMT2A Q03164 3/20 0.59
NPC1 O15118 2/20 0.59
TSHR P16473 2/20 0.57
PLK1 P53350 1/20 0.57
ALDH1A1 P00352 5/20 0.56
MAPT P10636 2/20 0.56
MAPK1 P28482 1/20 0.56
USP2 O75604 1/20 0.56
NFKB1 P19838 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2344909 0.85 GAA (0.71) GAASMN1; SMN2HTTKMT2ATSHR
SCHEMBL3365582 0.83 TERT (0.59) KDM4EGAASMN1; SMN2MPOHIF1A
SCHEMBL8015608 0.83 CA1 (0.61) KDM4EGAASMN1; SMN2MPOHIF1A
Salicylhydroxamic Acid SCHEMBL7072582 0.82 KDM4E (0.95) KDM4EGAASMN1; SMN2MPOHIF1A
SCHEMBL70688 0.81 KDM4E (0.71) KDM4EGAASMN1; SMN2MPOHIF1A
SCHEMBL77381 0.81 CA1 (0.77) KDM4EGAASMN1; SMN2MPOHIF1A
SCHEMBL14164188 0.81 PLK1 (0.52) KDM4EGAASMN1; SMN2MPOHIF1A
Salicylhydroxamic Acid SCHEMBL28084600 0.80 KDM4E (0.91) KDM4EGAASMN1; SMN2MPOHIF1A
SCHEMBL24445885 0.79 GAA (0.58) KDM4EGAASMN1; SMN2MPOHIF1A
SCHEMBL30737418 0.79 PLK1 (0.65) KDM4EGAASMN1; SMN2MPOHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 299 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118141701-A Composition containing benzoic acid derivative or furoic acid derivative and use of the derivative for emulsion and foam stability 西姆莱斯股份公司 2024-06-07 CN claimed
CN-109475120-B Antimicrobial compositions 西姆莱斯股份公司 2022-03-29 CN claimed
CN-112209861-A Acixtinib intermediate compound and preparation method thereof 鲁南制药集团股份有限公司 2021-01-12 CN claimed
CN-112209860-A Preparation method of axitinib intermediate 鲁南制药集团股份有限公司 2021-01-12 CN claimed
CN-108349949-A N- substituted indole derivatives as PGE2 receptor modulators 爱杜西亚药品有限公司 2018-07-31 CN claimed
EP-3074482-A1 ENCODED CHROMOPHORIC POLYMER PARTICLES University Of Washington Through Its Center For Commercialization (US) 2016-10-05 EP claimed
CN-105934498-A Encoded chromophoric polymer particles 华盛顿大学商业中心 2016-09-07 CN claimed
WO-2015081126-A1 ENCODED CHROMOPHORIC POLYMER PARTICLES UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2015-06-04 WO claimed
WO-2010146142-A9 METHODS AND COMPOUNDS FOR REDUCING ALLERGIC REACTIONS TO HAIR DYES HDS LIMITED (GB) 2011-06-16 WO claimed
US-20100069244-A1 Pyridine Compounds for Combating Pests BASF SE (DE) 2010-03-18 US claimed
US-20060149093-A1 Process for saparating a hydroxybenzonitrile-type compound RHODIA CHIMIE (FR) 2006-07-06 US claimed
EP-1289937-A1 METHOD FOR SEPARATING A HYDROXYBENZONITRILE-TYPE COMPOUND RHODIA CHIMIE (FR) 2003-03-12 EP claimed
US-6376548-B1 FUNGICIDES; HERBICIDES; INSECTICIDES ROHM AND HAAS COMPANY 2002-04-23 US claimed
WO-2001096284-A1 METHOD FOR SEPARATING A HYDROXYBENZONITRILE-TYPE COMPOUND RHODIA CHIMIE (FR) 2001-12-20 WO claimed
EP-1047690-A1 HETEROCYCLIC ETHER AND THIOETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION Abbott Laboratories (US) 2000-11-02 EP claimed
WO-1999032480-A1 HETEROCYCLIC ETHER AND THIOETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION ABBOTT LABORATORIES (US) 1999-07-01 WO claimed
EP-4749267-A2 CHROMOPHORIC POLYMER DOTS WITH NARROW-BAND EMISSION University of Washington Through Its Center for Commercialization (US) 2026-05-27 EP disclosed
EP-3718573-B1 CHROMOPHORIC POLYMER DOTS WITH NARROW-BAND EMISSION UNIV WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2026-05-20 EP disclosed
US-4100192-A Inter-phenylene-PG amides THE UPJOHN COMPANY (US) 1978-07-11 US disclosed
US-4097489-A PROSTAGLANDINS THE UPJOHN COMPANY (US) 1978-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060149093-A1 Process for saparating a hydroxybenzonitrile-type compound HPD, GNPAT, AGT KDM4E 2965/4885GAA 694/4885SMN1; SMN2 4096/4885
US-20100069244-A1 Pyridine Compounds for Combating Pests CHRM1, PRDX1, CHRM2 KDM4E 1115/4885GAA 4170/4885SMN1; SMN2 2630/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.