Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | F13A1 | P00488 | 1/20 | 0.41 |
| ▸ | TGM1 | P22735 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | FABP7 | O15540 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20104689 | 0.78 | ALDH1A1 (0.47) | ALDH1A1HCAR2TDP1MAPK1L3MBTL1 | |
| Benzene SCHEMBL28307095 | 0.73 | HCAR2 (0.65) | ALDH1A1HCAR2TGM2TDP1MAPK1 | |
| SCHEMBL9213185 | 0.73 | ALDH1A1 (0.62) | ALDH1A1HCAR2TDP1MAPK1L3MBTL1 | |
| SCHEMBL8923839 | 0.73 | ALDH1A1 (0.57) | ALDH1A1HCAR2TDP1MAPK1L3MBTL1 | |
| SCHEMBL28230354 | 0.73 | HCAR2 (0.65) | ALDH1A1HCAR2TGM2TDP1MAPK1 | |
| SCHEMBL34054 | 0.73 | HCAR2 (0.65) | ALDH1A1HCAR2TGM2TDP1MAPK1 | |
| SCHEMBL541750 | 0.73 | HCAR2 (0.51) | ALDH1A1HCAR2TGM2TDP1MAPK1 | |
| SCHEMBL8316594 | 0.73 | ALDH1A1 (0.50) | ALDH1A1HCAR2TDP1MAPK1L3MBTL1 | |
| SCHEMBL15229349 | 0.72 | ALDH1A1 (0.41) | ALDH1A1HCAR2TDP1MAPK1L3MBTL1 | |
| SCHEMBL8923844 | 0.72 | ALDH1A1 (0.56) | ALDH1A1HCAR2TDP1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2459565-B1 | SAXITOXIN DERIVATIVES, METHODS AND COMPOSITIONS FOR STUDYING, IMAGING, AND TREATING PAIN | UNIV LELAND STANFORD JUNIOR (US) | 2018-05-02 | — | — | EP | disclosed |
| US-20160115173-A1 | METHODS AND COMPOSITIONS FOR STUDYING, IMAGING, AND TREATING PAIN | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2016-04-28 | — | — | US | disclosed |
| US-20160115173-A1 | METHODS AND COMPOSITIONS FOR STUDYING, IMAGING, AND TREATING PAIN | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2016-04-28 | — | — | US | disclosed |
| US-9174999-B2 | Methods and compositions for studying, imaging, and treating pain | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2015-11-03 | — | — | US | disclosed |
| US-9174999-B2 | Methods and compositions for studying, imaging, and treating pain | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2015-11-03 | — | — | US | disclosed |
| WO-2010129864-A9 | METHODS AND COMPOSITIONS FOR STUDYING, IMAGING, AND TREATING PAIN | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2012-03-08 | — | — | WO | disclosed |
| US-20100284913-A1 | Methods and compositions for studying, imaging, and treating pain | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIO (US) | 2010-11-11 | — | — | US | disclosed |
| US-20100284913-A1 | Methods and compositions for studying, imaging, and treating pain | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIO (US) | 2010-11-11 | — | — | US | disclosed |
| WO-2010129864-A2 | METHODS AND COMPOSITIONS FOR STUDYING, IMAGING, AND TREATING PAIN | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2010-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160115173-A1 | METHODS AND COMPOSITIONS FOR STUDYING, IMAGING, AND TREATING PAIN | INA, SCN3A, SCN9A | ALDH1A1 4803/4885HCAR2 1592/4885TGM2 830/4885 |
| US-20100284913-A1 | Methods and compositions for studying, imaging, and treating pain | INA, SCN3A, SCN9A | ALDH1A1 4803/4885HCAR2 1592/4885TGM2 830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.