Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 5/20 | 0.49 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | KDM5C | P41229 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PPARD | Q03181 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31203953 | 1.00 | KDM5A (0.49) | KDM5APHF8KDM4CFAAHCES2 | |
| SCHEMBL31196596 | 1.00 | KDM5A (0.49) | KDM5APHF8KDM4CFAAHCES2 | |
| SCHEMBL31272261 | 1.00 | KDM5A (0.49) | KDM5APHF8KDM4CFAAHCES2 | |
| SCHEMBL31443267 | 1.00 | KDM5A (0.49) | KDM5APHF8KDM4CFAAHCES2 | |
| SCHEMBL7459318 | 1.00 | KDM5A (0.49) | KDM5APHF8KDM4CFAAHCES2 | |
| SCHEMBL25318796 | 1.00 | KDM5A (0.49) | KDM5APHF8KDM4CFAAHCES2 | |
| SCHEMBL25235788 | 1.00 | KDM5A (0.49) | KDM5APHF8KDM4CFAAHCES2 | |
| SCHEMBL25318391 | 1.00 | KDM5A (0.49) | KDM5APHF8KDM4CFAAHCES2 | |
| SCHEMBL20536250 | 1.00 | KDM5A (0.49) | KDM5APHF8KDM4CFAAHCES2 | |
| SCHEMBL31050946 | 1.00 | KDM5A (0.49) | KDM5APHF8KDM4CFAAHCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250206699-A1 | LIPID COMPOUNDS AND LIPID NANOPARTICLES | BROADPHARM INC. (US) | 2025-06-26 | — | — | US | disclosed |
| WO-2023178065-A2 | LIPID COMPOUNDS AND LIPID NANOPARTICLES | BROADPHARM INC. (US) | 2023-09-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250206699-A1 | LIPID COMPOUNDS AND LIPID NANOPARTICLES | PLIN1, NPC1L1, NPC1 | KDM5A 4456/4885PHF8 3855/4885KDM4C 4329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.