Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 15/20 | 0.49 |
| ▸ | CNR2 | P34972 | 15/20 | 0.49 |
| ▸ | HTR3A | P46098 | 3/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2541370 | 1.00 | CNR1 (0.49) | CNR1CNR2HTR3AHTR6LMNA | |
| SCHEMBL2540580 | 0.91 | DYRK1A (0.46) | CNR1CNR2HTR3ALMNAGAA | |
| SCHEMBL2540577 | 0.91 | DYRK1A (0.46) | CNR1CNR2HTR3ALMNAGAA | |
| SCHEMBL2546245 | 0.77 | CNR2 (0.47) | CNR1CNR2MAPTHTT | |
| SCHEMBL2546255 | 0.77 | CNR2 (0.47) | CNR1CNR2MAPTHTT | |
| SCHEMBL9171932 | 0.73 | CNR2 (0.64) | CNR1CNR2 | |
| SCHEMBL13239579 | 0.73 | L3MBTL1 (0.46) | HTR6LMNAGAAMAPTHTT | |
| SCHEMBL28072744 | 0.72 | CNR2 (0.69) | CNR1CNR2 | |
| SCHEMBL28437013 | 0.71 | CNR2 (0.68) | CNR1CNR2 | |
| SCHEMBL31516345 | 0.71 | CNR1 (0.44) | CNR1CNR2HTR6LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8309550-B2 | Kinase inhibitors and their use as pharmaceutical agents | SHANGHAI GENOMICS, INC. (CN) | 2012-11-13 | — | — | US | disclosed |
| US-20110263541-A1 | KINASE INHIBITORS AND THEIR USE AS PHARMACEUTICAL AGENTS | SHANGHAI GENOMICS, INC (CN) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263541-A1 | KINASE INHIBITORS AND THEIR USE AS PHARMACEUTICAL AGENTS | MAP3K20, MAP3K1, MAP3K2 | CNR1 2435/4885CNR2 2281/4885HTR3A 3199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.