SCHEMBL25414267

SCHEMBL25414267

C=CCO[C@H]1O[C@H](COC(=O)OCc2ccccc2)[C@@H](O)[C@H](OCc2ccccc2)[C@H]1NC(=O)OCC(Cl)(Cl)Cl

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ MCHR1 Q99705 13/20 0.39
▸ SSTR5 P35346 6/20 0.39
▸ SSTR3 P32745 5/20 0.39
▸ SSTR2 P30874 3/20 0.39
▸ SSTR1 P30872 1/20 0.39
▸ SSTR4 P31391 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2797352 0.92 SSTR4 (0.42) MCHR1SSTR5SSTR3SSTR2SSTR1
SCHEMBL2797350 0.92 SSTR4 (0.42) MCHR1SSTR5SSTR3SSTR2SSTR1
SCHEMBL25412287 0.90 SLC6A2 (0.43) MCHR1SSTR5SSTR3SSTR2SSTR1
SCHEMBL25412293 0.90 SLC6A2 (0.43) MCHR1SSTR5SSTR3SSTR2SSTR1
SCHEMBL25414374 0.87 LMNA (0.34) MCHR1SSTR5SSTR3
SCHEMBL7144653 0.85 TLR4 (0.36) MCHR1SSTR5SSTR3SSTR2
SCHEMBL13231369 0.85 TACR2 (0.39) MCHR1SSTR5SSTR3SSTR2SSTR1
SCHEMBL2798128 0.85 TACR2 (0.39) MCHR1SSTR5SSTR3SSTR2SSTR1
SCHEMBL2798123 0.85 TACR2 (0.39) MCHR1SSTR5SSTR3SSTR2SSTR1
SCHEMBL7136889 0.82 SLC5A1 (0.36) MCHR1SSTR5SSTR3SSTR2SSTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240002425-A1 NOVEL AMINOALKYL GLUCOSAMINIDE 4-PHOSPHATE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2024-01-04 — — US disclosed
EP-4245763-A1 NOVEL AMINOALKYL GLUCOSAMINIDE 4-PHOSPHATE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2023-09-20 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240002425-A1 NOVEL AMINOALKYL GLUCOSAMINIDE 4-PHOSPHATE DERIVATIVE TLR4, TLR5, TLR9 MCHR1 3247/4885SSTR5 2455/4885SSTR3 3270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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