Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4331680 | 0.72 | KIF11 (0.34) | TSHRMAPK1S1PR1 | |
| SCHEMBL2145857 | 0.72 | PDE2A (0.34) | TSHRMAPK1S1PR1 | |
| SCHEMBL7412520 | 0.69 | TSHR (0.31) | TSHRMAPK1S1PR1 | |
| SCHEMBL17816206 | 0.69 | KIF11 (0.37) | TSHRMAPK1S1PR1 | |
| SCHEMBL19191095 | 0.68 | TACR1 (0.34) | TSHRMAPK1 | |
| SCHEMBL2331693 | 0.67 | DRD4 (0.40) | — | |
| SCHEMBL2334903 | 0.65 | S1PR1 (0.53) | TSHRS1PR1 | |
| SCHEMBL11818712 | 0.64 | PTPN5 (0.35) | TSHRMAPK1S1PR1 | |
| SCHEMBL4901404 | 0.63 | KIF11 (0.45) | — | |
| SCHEMBL16505901 | 0.63 | CFTR (0.49) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023169573-A1 | POLθ INHIBITOR | 武汉人福创新药物研发中心有限公司 | 2023-09-14 | — | — | WO | disclosed |
| CN-116730979-A | Pol theta inhibitor | 武汉人福创新药物研发中心有限公司 | 2023-09-12 | — | — | CN | disclosed |