Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2277430 | 0.77 | NR1H2 (0.44) | NR1H2CHRM2CHRM1CHRM3USP2 | |
| SCHEMBL30700601 | 0.76 | NR1H2 (0.48) | NR1H2CHRM2CHRM1CHRM3SMN1; SMN2 | |
| SCHEMBL16584672 | 0.76 | NR1H2 (0.48) | NR1H2CHRM2CHRM1CHRM3SMN1; SMN2 | |
| SCHEMBL24909283 | 0.76 | NR1H2 (0.48) | NR1H2CHRM2CHRM1CHRM3SMN1; SMN2 | |
| SCHEMBL609610 | 0.76 | NR1H2 (0.48) | NR1H2CHRM2CHRM1CHRM3SMN1; SMN2 | |
| SCHEMBL609346 | 0.76 | NR1H2 (0.48) | NR1H2CHRM2CHRM1CHRM3SMN1; SMN2 | |
| SCHEMBL15996597 | 0.75 | CHRM2 (0.46) | NR1H2CHRM2CHRM1CHRM3USP2 | |
| SCHEMBL25510610 | 0.75 | CHRM2 (0.46) | NR1H2CHRM2CHRM1CHRM3USP2 | |
| SCHEMBL19296178 | 0.75 | CHRM2 (0.46) | NR1H2CHRM2CHRM1CHRM3USP2 | |
| SCHEMBL14899628 | 0.75 | CHRM2 (0.46) | NR1H2CHRM2CHRM1CHRM3USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4713320-A2 | BCAT2 INHIBITORS | Agios Pharmaceuticals, Inc. (US) | 2026-03-25 | — | — | EP | disclosed |
| WO-2024238820-A2 | BCAT2 INHIBITORS | AGIOS PHARMACEUTICALS, INC. (US) | 2024-11-21 | — | — | WO | disclosed |
| EP-4430036-A2 | BCAT2 INHIBITORS | Agios Pharmaceuticals, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023086539-A2 | BCAT2 INHIBITORS | AGIOS PHARMACEUTICALS, INC. (US) | 2023-05-19 | — | — | WO | disclosed |