Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 4/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.32 |
| ▸ | FASN | P49327 | 1/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | CDK7 | P50613 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.30 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.30 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.30 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.30 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.30 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.30 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25554653 | 0.94 | KDM1A (0.33) | KDM1APRMT5EGLN1CYP19A1CYP11B1 | |
| SCHEMBL25555980 | 0.94 | KDM1A (0.33) | KDM1APRMT5EGLN1CYP19A1CYP11B1 | |
| SCHEMBL25555995 | 0.88 | NSD2 (0.33) | NSD2KDM1AALOX5APFEN1DYRK3 | |
| SCHEMBL30353119 | 0.87 | KDM1A (0.37) | NSD2KDM1AALOX5APFEN1CYP19A1 | |
| SCHEMBL25554348 | 0.87 | KDM1A (0.37) | NSD2KDM1AALOX5APFEN1CYP19A1 | |
| SCHEMBL25554560 | 0.87 | NSD2 (0.34) | NSD2KDM1AEGLN1ALOX5APFEN1 | |
| SCHEMBL25554649 | 0.86 | EGLN1 (0.33) | PRMT5EGLN1FASNCYP19A1CYP11B1 | |
| SCHEMBL25555964 | 0.85 | LRRK2 (0.34) | NSD2KDM1AEGLN1ALOX5APFEN1 | |
| SCHEMBL30257252 | 0.81 | NSD2 (0.39) | NSD2KDM1ACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL25554341 | 0.81 | NSD2 (0.39) | NSD2KDM1ACYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167073-A1 | ARYL OR HETEROARYL DERIVATIVE | TEIJIN PHARMA LIMITED (JP) | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167073-A1 | ARYL OR HETEROARYL DERIVATIVE | ARRB1, NR3C2, TRPC6 | NSD2 3265/4885KDM1A 4415/4885PRMT5 4344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.