SCHEMBL25417762

SCHEMBL25417762

COC(=O)c1ccc2nc(-c3cc(OC)cc(OC)c3)c(N)n2c1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ TRIM33 Q9UPN9 10/20 0.48
▸ TRIM24 O15164 3/20 0.47
▸ AKT1 P31749 1/20 0.47
▸ AKT2 P31751 1/20 0.47
▸ NPC1 O15118 1/20 0.45
▸ MAPT P10636 1/20 0.45
▸ RAB9A P51151 1/20 0.45
▸ CDK4 P11802 2/20 0.43
▸ CDK2 P24941 2/20 0.43
▸ BRD4 O60885 1/20 0.42
▸ ALPG P10696 1/20 0.41
▸ F2 P00734 1/20 0.41
▸ CYP11B1 P15538 1/20 0.40
▸ CYP11B2 P19099 1/20 0.40
▸ CA1 P00915 1/20 0.40
▸ CA2 P00918 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25417063 0.83 AKT1 (0.46) TRIM33AKT1AKT2F2CYP11B1
SCHEMBL25415556 0.74 HSD17B10 (0.42) MAPTF2
SCHEMBL25416724 0.74 AKT1 (0.51) TRIM33AKT1AKT2NPC1MAPT
SCHEMBL25415154 0.73 NPC1 (0.53) NPC1MAPTRAB9ABRD4
SCHEMBL2127536 0.70 AKT1 (0.58) TRIM33TRIM24AKT1AKT2NPC1
SCHEMBL25416172 0.70 AKT1 (0.45) AKT1AKT2MAPT
SCHEMBL7466484 0.69 AKT1 (0.60) AKT1AKT2NPC1MAPTRAB9A
SCHEMBL3500174 0.69 SLC2A1 (0.50) TRIM33AKT1AKT2MAPTBRD4
SCHEMBL26931747 0.69 BRD4 (0.51) TRIM33TRIM24AKT1AKT2NPC1
SCHEMBL11263888 0.69 ALPG (0.82) TRIM33TRIM24ALPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260071117-A1 FUNABLE FLUORESCENT COMPOUNDS AND USES THEREOF UNIV ARIZONA (US) 2026-03-12 — — US disclosed
WO-2023081261-A1 TUNABLE FLUORESCENT COMPOUNDS AND USES THEREOF ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2023-05-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260071117-A1 FUNABLE FLUORESCENT COMPOUNDS AND USES THEREOF H1-3, NISCH, H1-2 TRIM33 3976/4885TRIM24 2239/4885AKT1 3389/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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