SCHEMBL25416172

SCHEMBL25416172

COC(=O)c1ccn2c(N)c(-c3cc(OC)c(OC)c(OC)c3)nc2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AKT1 P31749 1/20 0.45
▸ AKT2 P31751 1/20 0.45
▸ PDGFRB P09619 1/20 0.43
▸ ADORA3 P0DMS8 2/20 0.42
▸ TUBB4A P04350 5/20 0.41
▸ TUBB P07437 5/20 0.41
▸ TUBA3C P0DPH7 5/20 0.41
▸ TUBA1B P68363 5/20 0.41
▸ TUBA4A P68366 5/20 0.41
▸ TUBB4B P68371 5/20 0.41
▸ TUBB3 Q13509 5/20 0.41
▸ TUBB2A Q13885 5/20 0.41
▸ TUBB8 Q3ZCM7 5/20 0.41
▸ TUBA3E Q6PEY2 5/20 0.41
▸ TUBA1A Q71U36 5/20 0.41
▸ TUBA1C Q9BQE3 5/20 0.41
▸ TUBB6 Q9BUF5 5/20 0.41
▸ TUBB2B Q9BVA1 5/20 0.41
▸ TUBB1 Q9H4B7 5/20 0.41
▸ NEK2 P51955 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25417063 0.86 AKT1 (0.46) AKT1AKT2ADORA3PTK2PLAU
SCHEMBL25416724 0.84 AKT1 (0.51) AKT1AKT2TUBB4ATUBBTUBA3C
SCHEMBL17114242 0.83 AKT1 (0.60) AKT1AKT2PTK2PLAUKDM4E
SCHEMBL25417148 0.81 AKT1 (0.61) AKT1AKT2PLAUKDM4E
SCHEMBL25416745 0.80 TLR9 (0.42) AKT1AKT2ADORA3PLAU
SCHEMBL25415193 0.80 AKT1 (0.52) AKT1AKT2PTK2PLAU
SCHEMBL25416077 0.77 MEN1 (0.51) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL25415908 0.77 AKT1 (0.54) AKT1AKT2PTK2PLAU
SCHEMBL25416128 0.77 AKT1 (0.47) AKT1AKT2PLAUMAPTKDM4E
SCHEMBL25415463 0.77 TUBB4A (0.61) TUBB4ATUBBTUBA3CTUBA1BTUBA4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260071117-A1 FUNABLE FLUORESCENT COMPOUNDS AND USES THEREOF UNIV ARIZONA (US) 2026-03-12 — — US disclosed
WO-2023081261-A1 TUNABLE FLUORESCENT COMPOUNDS AND USES THEREOF ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2023-05-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260071117-A1 FUNABLE FLUORESCENT COMPOUNDS AND USES THEREOF H1-3, NISCH, H1-2 AKT1 3389/4885AKT2 3506/4885PDGFRB 4698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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