Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.35 |
| ▸ | TCF7L2 | Q9NQB0 | 4/20 | 0.35 |
| ▸ | PIM1 | P11309 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 2/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | BCL6 | P41182 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL31485475 | 1.00 | HTT (0.47) | HTTMAPTCTNNB1TCF7L2PIM1 | |
| Formic Acid SCHEMBL31148455 | 1.00 | HTT (0.47) | HTTMAPTCTNNB1TCF7L2PIM1 | |
| SCHEMBL30422535 | 0.97 | HTT (0.49) | HTTMAPTCTNNB1TCF7L2PIM1 | |
| SCHEMBL31148423 | 0.89 | BCL6 (0.41) | HTTMAPTBCL6 | |
| Formic Acid SCHEMBL31148383 | 0.87 | MAPT (0.40) | MAPTWDR5PTPN11POLB | |
| SCHEMBL25211482 | 0.87 | MAPT (0.41) | HTTMAPTPTPN11POLB | |
| SCHEMBL30422832 | 0.87 | MAPT (0.41) | HTTMAPTPTPN11POLB | |
| Formic Acid SCHEMBL31148429 | 0.87 | ROCK2 (0.38) | HTTMAPTROCK2PTPN11POLB | |
| Formic Acid SCHEMBL31148466 | 0.87 | PTPN11 (0.36) | HTTMAPTWDR5PTPN11POLB | |
| Formic Acid SCHEMBL31148399 | 0.87 | PTPN11 (0.36) | HTTMAPTWDR5PTPN11POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023102231-A1 | 5-PYRIMIDINECARBOXAMIDE DERIVATIVES AND METHODS OF USING THE SAME | RGENTA THERAPEUTICS, INC. (US) | 2023-06-08 | — | — | WO | disclosed |