Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 4/20 | 0.31 |
| ▸ | CA2 | P00918 | 4/20 | 0.31 |
| ▸ | CA12 | O43570 | 3/20 | 0.31 |
| ▸ | CA7 | P43166 | 3/20 | 0.31 |
| ▸ | CA9 | Q16790 | 3/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2535165 | 0.85 | MAPT (0.41) | TSHRLMNAALOX15ALDH1A1TRPA1 | |
| SCHEMBL9681621 | 0.80 | TSHR (0.40) | TSHRLMNAALOX15HCAR2ALDH1A1 | |
| SCHEMBL28897693 | 0.79 | TSHR (0.43) | TSHRLMNAALOX15HCAR2ALDH1A1 | |
| SCHEMBL6063173 | 0.79 | TSHR (0.43) | TSHRLMNAALOX15HCAR2ALDH1A1 | |
| SCHEMBL580557 | 0.79 | TSHR (0.43) | TSHRLMNAALOX15HCAR2ALDH1A1 | |
| SCHEMBL17617132 | 0.79 | TSHR (0.43) | TSHRLMNAALOX15HCAR2ALDH1A1 | |
| SCHEMBL13541326 | 0.79 | TSHR (0.43) | TSHRLMNAALOX15HCAR2ALDH1A1 | |
| SCHEMBL684789 | 0.79 | TSHR (0.43) | TSHRLMNAALOX15HCAR2ALDH1A1 | |
| SCHEMBL1866475 | 0.79 | TSHR (0.43) | TSHRLMNAALOX15HCAR2ALDH1A1 | |
| SCHEMBL3420611 | 0.77 | TSHR (0.42) | TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1982978-B1 | PYRIDONE DERIVATIVE AND HERBICIDE | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2014-08-27 | — | — | EP | disclosed |
| US-8076487-B2 | Pyridone derivative and herbicide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2011-12-13 | — | — | US | disclosed |
| US-8044070-B2 | Heteroaryloxy nitrogenous saturated heterocyclic derivative | MSD K.K. (JP) | 2011-10-25 | — | — | US | disclosed |
| US-20100222592-A1 | Pyridone Derivative and Herbicide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-09-02 | — | — | US | disclosed |
| US-20100210637-A1 | HETEROARYLOXY NITROGENOUS SATURATED HETEROCYCLIC DERIVATIVE | MSD K.K. (JP) | 2010-08-19 | — | — | US | disclosed |
| US-7595316-B2 | Heteroaryloxy nitrogenous saturated heterocyclic derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-09-29 | — | — | US | disclosed |
| EP-1982978-A1 | PYRIDONE DERIVATIVE AND HERBICIDE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2008-10-22 | — | — | EP | disclosed |
| US-20060178375-A1 | Heteroaryloxy nitrogenous saturated heterocyclic derivative | MSD K.K. (JP) | 2006-08-10 | — | — | US | disclosed |
| EP-1642898-A1 | HETEROARYLOXY NITROGENOUS SATURATED HETEROCYCLIC DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-04-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178375-A1 | Heteroaryloxy nitrogenous saturated heterocyclic derivative | HRH3, HRH4, HCRTR2 | TSHR 226/4885LMNA 3909/4885ALOX15 1450/4885 |
| US-20100210637-A1 | HETEROARYLOXY NITROGENOUS SATURATED HETEROCYCLIC DERIVATIVE | HRH3, HRH4, HRH2 | TSHR 223/4885LMNA 3913/4885ALOX15 1059/4885 |
| US-20100222592-A1 | Pyridone Derivative and Herbicide | PDXK, PNPO, CBR3 | TSHR 2120/4885LMNA 3316/4885ALOX15 2601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.